The Open Targets Platform REST API provides programmatic access to integrated genetic and clinical evidence linking targets to diseases for drug discovery research. Endpoints fall into public methods (stable, fully supported) for associations, evidence, and search; private methods used by the Open Targets web app for autocomplete, drug, disease, and target detail; and utils for service metrics and version info. Responses are JSON by default with optional xml, csv, and tab formats on some endpoints. The API is openly accessible and is the standard programmatic entry point for the Open Targets Platform's curated bioinformatics data.
The Open Targets Platform REST API serves the evidence linking genes and diseases for drug target discovery. An agent can search across targets, diseases, and drugs, retrieve the association between a target and a disease, read the underlying evidence, and pull platform statistics. It suits biomedical research and drug-discovery work that needs structured target-disease evidence rather than a manual literature review. The API is read-oriented and needs no credentials.
Step 1: Jentic One Host machine
# On the machine that will host your Jentic One instance:
curl -fsSL "https://jentic.com/install.sh?src=apis&api=%2Fapis%2Fopentargets.io" | shStep 2: Agent machine
# On the machine where your agent runs (keep this separate from the instance):
curl -fsSL "https://jentic.com/install.sh?src=apis&api=%2Fapis%2Fopentargets.io" | sh
jentic register # connects your agent to your Jentic One instanceJentic One is in public beta. The setup above keeps your agent separate from the instance, which is what you want before using real credentials: an agent running as the same OS user as Jentic One can read its stored keys directly. Just evaluating? A single local install is fine to start. See the secure deployment guide for the tiers.
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